PROBIOTICS

Biopolis has capabilities from sourcing and screening of novel strains, to preclinical and clinical evaluation, scale-up and industrial manufacturing of probiotics.
The Company has developed both proprietary and tailored strains for its partners and produces several tons of probiotics every year.

WE COVER THE WHOLE PROCESS

1

DISCOVERY

2

EVALUATION

3

UPSCALING

4

PRODUCTION

In Biopolis we screen, select and isolate top strains for our clients.

Genome sequencing of all our strains is performed at Biopolis facilities.

All our strains are included in QPS lists.

Evaluated in vitro and in vivo following the FAO/WHO guidelines.

Production in lab fermentors is scaled up with Biopolis strains before industrial fermentation.

Production process optimization means we can sell and ensure long shelf-life, adapting to customer demands.

Specific production requirements of each client and compound.

OUR SERVICES

NOVEL PROBIOTICS

FUNCTIONAL EVALUATION

SAFETY EVALUATION

  • Isolation of biologic samples
  • Identification
  • Characterization
  • In vitro assays
  • Caenorhabditis elegans
  • Mechanisms of action
  • In vitro assays
  • In vitro (murine models)
  • Studies for GRAS self-affirmation and EFSA
  • FAO/WHO Safety guidelines
  • Whole genome sequencing

UPSCALING

MANUFACTURING

FURTHER EVALUATION

  • 1/2/5 L fermentors
  • Culture and liophilization optimization
  • GMP production
  • 1,500 & 3,000 L fermentation
  • Gluten, lactose and milk protein free
  • GMO free
  • Bulk powder production
  • Gallenic production
  • Microbiome
  • Murine models
  • Clinical trials
  • Patentability

OUR COMPETITIVE ADVANTAGES

  • BUSINESS ORIENTED APPROACH

  • FULL CONFIDENTALITY BASIS

  • VALUE CHAIN

  • CLOSE INTERACTIONS WITH CUSTOMERS

  • INTERDISCIPLINARY TEAM

  • OMIC TECHNOLOGIES

  • ESTABLISHED PARTENRSHIPS WITH TOP PLAYERS IN THE INDUSTRY

OUR TARGETS

IMMUNE SYSTEM

DIGESTIVE HEALTH

WOMEN HEALTH

SKIN HEALTH

WEIGHT MANAGEMENT

BABY & KIDS HEALTH

SPORTS NUTRITION

SENIORS HEALTH

Would you like to know more?

Have a look at our portfolio