Novel Ingredients

Biopolis has developed proprietary functional ingredients and has helped its partners in the development of their own products.
Our experiments are based in the use of the Caenorhabditis elegans preclinical model supported by in vitro assays for the evaluation of novel food and pharmaceutical active ingredients.

WE COVER THE WHOLE VALUE CHAIN

INGREDIENTS

IN VITRO

ASSAYS

PRE-CLINICAL

ASSAYS

TECHNOLOGICAL

ADAPTATION

CLINICAL TRIALS

MICROORGANISMS

PEPTIDES

LIPIDS

FIBERS

POLIPHENOLS

PROBIOTICS…

ENZYMATIC ASSAYS

CELL CULTURES

C. ELEGANS MODEL

MURINE MODELS

MATRIX ADDITION

BIODISPONIBILITY

SHELF-LIFE

MANAGING

MAIN ACTIVITIES

BIOCHEMISTRY APPLICATIONS

MICROBIOLOGY SOLUTIONS

  • Generation and development of new ingredients
  • Characterization of ingredients or products
  • In vitro assays (functional and technological approach)
  • Food safety/evaluation (in vitro & in vivo)
  • Generation and development of new ingredients
  • In vitro assays (Functional and technological approach)
  • Food safety/ evaluation (in vitro & in vivo)
  • Development of tailored molecular methodologies (RT-PCR)
  • Fecal slurries
  • Microbiome analysis

C. elegans  MODEL

FURTHER EVALUATION

  • Functional evaluation of ingredients in C. elegans in vivo model
  • Functional targets: obesity, antioxidant, ageing, diabetes, neurodegenerative disease, cognitive function, immune boosting and dermocosmetics
  • Toxicological studies in C. elegans (LD50)
  • Mechanism of action (transcriptomics, metabolomics mutants)
  • Automated systems for highthouput screening
  • Murine models
  • Clinical trials
  • Patentability

OUR COMPETITIVE ADVANTAGES

  • BUSINESS ORIENTED APPROACH

  • FULL CONFIDENTIALITY BASIS

  • PRESENCE THROUGHOUT THE VALUE CHAIN

  • CLOSE INTERACTION WITH CUSTOMERS

  • INTERDISCIPLINARY TEAM

  • OMIC TECHNOLOGIES

  • TAILOR-MADE RESEARCH

  • ROBUST AND SOLID RESULTS

  • C. ELEGANS REFERENCE COMPANY FOR THE INDUSTRY

8 RESEARCH AREAS

OBESITY

ANTIOXIDANT EFFECT

AGING

DIABETES

NEURODEGENERATIVE DISEASE

COGNITIVE FUNCTION

IMMUNE BOOSTING

DERMOCOSMETICS

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